Paget’s Disease: Episode 120

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Paget’s Disease

  • Paget’s Disease causes bones too soften due to over activation of osteoclasts. Osteoclasts are responsible for breaking down bone. In response to this the body attempts to quickly lay down new bone. Which causes enlargement of the bone, typically the spine, skull and long bones are most affected.

  • Chip Review @ (10:25): Kroger – Kettle Cooked – Nashville Style Hot Chicken (Thank you Mimi DeRose)

  • Trivia question of the week @ (08:24): Which teams played in the first NHL game?

  • Follow us on Instagram: 2pts_n_a_bagofchips and/or Twitter @2PTsNaBagOChips to see photos, video and get additional episode specific information throughout the week.

  • Thanks for listening!!

   

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Brief overview of the episode:

            Paget’s Disease is a rare bone disease that affects less than 1% of the population. There is over activation of osteoclasts (which break down bone). This result in the body trying to quickly rebuild build bone. However, the over response causes the new bone to soft and enlarged. This process is known as rapid isolated bone growth.

            The good news is this disease is very rare, affecting less than 1% of the population, and in most cases is highly manageable. The prevalence is 3:2 men to women and is more common as we age.

            Symptoms include pain in bones and joints, headache, hearing impairment, enlarged bones, bowing bones, numbness & tingling, difficulty bending over and fractures. Most commonly the long bones, spine and skull are impacted.

 

Other episodes you might enjoy:

Avascular Necrosis: Episode 68
Osteoarthritis & Rheumatoid Arthritis: Episode 57
Nutrition for Recovery with Amanda Turner: Episode 44

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